Scientific References

Backed by Veterinary Science

PuppyZest® is formulated and produced to the highest standards, using ingredients selected and in combination with each other based on extensive species specific research and clinical evidence. Every component is chosen for its proven ability to support canine neonatal health, ensuring that each dose delivers scientifically-backed nutrition and care for puppies in their most critical stages of development.

Scientific References
Scientific References
Scientific References

Nutritional Gain at a glance

Glucose & DHA for Cognitive Development

PuppyZest® contains a measured amount of glucose providing balanced and immediately available energy resource critical for the first 24 hours. (A1, A2) Research also highlights DHA’s critical role in supporting normal brain function and visual development in early life. Algae derived Omega oil offers a source of DHA supporting normal neurological and nervous system health, eye health and the cardiovascular system. Algal oil supports gut microbiota and the intestinal barrier to facilitate normal gut function. (A2)

Colostrum & Immunity

Studies show colostrum’s role in boosting passive immunity (B2) which provides neonates with normal defenses. PuppyZest provides an essential supplementary source of IgG maternal antibodies which assists and compliment normal passive immunity, critical in the first few hours of life. (B1) Colostrum also provides a source of protein providing the necessary building blocks for a healthy start and maintaining a healthy intestinal lining.

Probiotic Stability

Evidence supports probiotics' ability to stabilize gut health and return normal digestive function in neonatal pups. Saccharomyces cerevisae in PuppyZest® provides the body with a natural probiotic which adsorbs pathogenic bacteria benefiting the puppy’s natural gut flora anti-microbial defenses. (P2) In addition, Saccharomyces cerevisae maintains normal gastrointestinal health which can be affected by dietary changes (P3) Enterococcus faecium is included and helps colonize the gut with beneficial bacteria. (P1)

Nutritional Zest & Essential Vitamins

PuppyZest® contains botanical extracts (Z1, Z2, Z3) which helps return normal sensory responses. In addition, select vitamins which provide a supplemental source for supporting normal vision, bone growth, cellular differentiation and the immune response. (V1, V2)

References & Bibliography

(A1) Neonatal hypoglycemia in dogs—pathophysiology, risk factors, diagnosis and treatment

(A2) Canine Colostrum

(A2) Nutrient Requirements of Dogs & Cats.

(B1) Perspectives on Immunoglobulins in Colostrum and Milk 

(B2) Passive immune transfer in puppies

(P1) Experimental addition of Eleutherococcus senticosus and probiotic to the canine diet.

(P2) Effect of a Saccharomyces cerevisiae fermentation product supplemented diet on circulating immune cells and oxidative stress markers of dogs.

(P3) Effect of Yeast Saccharomyces cerevisiae as a Probiotic on Diet Digestibility, Fermentative Metabolites, and Composition and Functional Potential of the Fecal Microbiota of Dogs Submitted to an Abrupt Dietary Change. 

(Z1) Clinical and Immunological Response in Dogs Naturally Infected by L. infantum Treated with a Nutritional Supplement.

(Z2) Effects of Eleutherococcus on the biorhythm of indices of peripheral blood in dogs

(Z3) Safety and efficacy of a feed additive consisting of a tincture derived from the roots of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (taiga root tincture) for use in dogs, cats and horses (FEFANA asbl)

(V1) Safety evaluation of vitamin A in growing dogs

Understanding the canine intestinal microbiota and its modification by pro‐, pre‐ and synbiotics – what is the evidence?

Committed to sustainability for pets and the planet

Member of Pet Sustainability Coalition

PuppyZest® is proud to be a member of the Pet Sustainability Coalition, a group dedicated to promoting sustainability within the pet industry. As part of this coalition, we commit to responsible sourcing, eco-friendly production methods, and ensuring that our products support the health of both pets and the planet.